Ctcf和ctcfl
WebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they … Web我们为您找到 ctcf 的 1 个相关产品结果。 ... 生命科学基础与转化研究的主要领域，包括细胞生物学、肿瘤、免疫与炎症、表观遗传学和转录调控、代谢与内分泌、衰老、心血管、干细胞和发育、神经科学、蛋白质翻译后修饰等，还提供病理学研究与伴随诊断 ...
Ctcf和ctcfl
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WebJun 22, 2024 · CTCF is a key organizer of the 3D genome. Its specialized paralog, BORIS, heterodimerizes with CTCF but is expressed only in male germ cells and in cancer states. WebCTCF-mediated enhancer blocking is conserved from Drosophila to man (Moon et al. 2005) Antisense transcription of triplet repeats is constrained by CTCF (Cho et al. 2005) Boundaries between X inactivation and escape of inactivation bind CTCF (Filippova et al. 2005) CTCF antagonizes with CTCFL at the cancer testis gene MAGE-A1 (Vatolin et al. …
WebJan 5, 2024 · CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional knock out (cKO) study revealed reactive gliosis of astrocytes and microglia followed by age-dependent cell death in the excitatory neurons … WebCTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is normally transiently …
WebApr 10, 2024 · CTCF (CCCTC-binding factor)是一种重要的染色质架构蛋白,其与绝缘子的方向性结合在哺乳动物基因组三维空间结构形成和维持中起着至关重要的作用。. 正向-反 … WebNov 30, 2010 · Function. Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by …
WebApr 1, 2024 · CTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is …
Web5.1 CTCF genome organizer and the cohesin complex. CTCF (CCCTC-binding factor) is a multiple zinc finger protein that exerts diversified functions under different genomic … helen inovasi sukses sentosaWebJun 18, 2012 · CTCFL acts as a male germ cell gene regulator, preferably binding near promoters with active chromatin marks. Interestingly, CTCF and CTCFL bind a highly … helen hunt jackson quotesWebWidespread expression of BORIS/CTCFL in normal and cancer cells. BORIS (CTCFL) is the paralog of CTCF (CCCTC-binding factor; NM_006565), a ubiquitously expressed … helen hobson mamma miaWebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they termed BORIS. The deduced 663-amino acid protein contains 11 central ZFs, like CTCF, but it has unique N and C termini. EMSA analysis showed an interaction with testis DNA. helen hyattWebMay 11, 2024 · CTCFL and CTCF-CTCFL overlapping binding sites are frequently bound by both CLC and LCL (Fig. 4 d, e), but at some locations, fusion protein peaks are reduced in size compared to that of CTCFL (e.g., at Ctcfl, Prss50, Gal3st1 loci) (Fig. 4 d). Sites bound by CTCF only were preferentially bound by LCL as opposed to CLC (Fig. 4 f). helen hunt jumanjiWebStatistical differences between individual binding categories (CTCFL, CTCF/CTCFL co-bound and CTCF or CTCFL stand-alone sites) and the average CTCF site as reference were calculated by Wilcoxon signed rank test (two-sided alternative: ‘binding in analyzed category is greater than that of CTCF binding’). The corresponding code is available ... helen hunt jackson poetryWebCTCFL Antibodies. Antibodies that detect CTCFL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, … helen hyslop