WebCytarabine (also called cytosine arabinoside or Ara-C) is a treatment for leukaemia, particularly acute myeloid leukaemia (AML). It can be administered at different doses, generally referred to as ‘high’, ‘intermediate’ and ‘low’. High and intermediate dose cytarabine are generally used as part of the intensive chemotherapy treatment Web11 de abr. de 2024 · Currently, high doses of cytarabine arabinoside (Ara-C)-based combined chemotherapy are commonly used in acute myeloid leukemia (AML) therapy, but severe adverse effects and poor suppression effects in leukemia cells limit the clinical therapeutic efficiency of Ara-C-based chemotherapy due to a lack of targeting selectivity. …
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Web30 de nov. de 2024 · Ara-C remains one of the most effective drugs used in the treatment of acute leukemia and other hematopoietic malignancies. In particular, high-dose ara-C is used during remission induction or as consolidation therapy after complete remission of acute myeloid leukemia in adults. Ara-C has also been used as an antiviral agent, … something big this way comes
Ara-C - Drug Information - Chemocare
WebDose-related effects of ara-C include overcoming a relative transport impediment in human leukemia cells. This result then allows intracellular metabolism and incorporation into … WebCytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). High-dose cytarabine (2000 to 3000 mg per square meter of body-surface area) is toxic … GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma F. Del Bufal… H.-J. Wang and S.C.-S. Hu N Engl J Med 2024; 388:1031-1031 A 30-year-old wo… Explore a collection of articles and other resources on the Coronavirus (Covid-19… Unfortunately, the prevalence of this common, costly, and painful condition is incr… Image Challenge from the New England Journal of Medicine — April 13, 2024 WebHigh-dose cytarabine (HD araC) therapy resulted from a theoretical model developed in the 1970s that attempted to maximize the anti-leukemia effect of cytarabine. Since that time, … small chick fil a cup