WebRated 5 out of 5 by JM from McMillin McMillin, M. et al. (PubMed 25012628) induced hepatic encephalopathy in mice via injection of azoxymethane (AOM) in the presence or absence of INCB 3284, a CCR2 inhibitor, or CCR4 Antagonist (C021). Mice were monitored for neurological decline and time to coma was recorded. They found that administration … WebINCB 3284 dimesylate is a potent, selective hCCR2 antagonist. Exhibits potent antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity (IC 50 values are 3.7 and 4.7 nM respectively). Also displays weak hERG activity; inhibits the hERG potassium current (IC 50 = 84 μ M). Orally bioavailable. Technical Data M.Wt:
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WebINCB 3284 dimesylate is a potent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC 50 of 3.7 nM. INCB 3284 dimesylate can be used in the research of acute liver failure. In vitro activity INCB3284 is a potent hCCR2 antagonist with IC 50 WebINCB 3284 dimesylate: Catalog No.: GC14821: HCCR2 antagonist. Size Price Stock Qty; 10mg $114.00. Ship Within 10-14 Days 50mg $522.00. Ship Within 10-14 Days ... WebJul 16, 2024 · Zestimate® Home Value: $28,000. 3284 Burlingame St, Detroit, MI is a single family home that contains 1,620 sq ft and was built in 1923. It contains 3 bedrooms and 1 … graham county assessor office